Seventeen subjects dropped out during treatment, were withdrawn from their protocol, or were just lost to follow-up.
Of the remaining subjects, the CBT (7.0%) and combination treatment (5.5%) groups had significantly smaller proportions of winter depression recurrences than the light therapy group (36.7%).
Additionally, CBT alone, but not combination treatment, was also associated with significantly lower interviewer- and patient-rated depression severity at 1 year as compared to light therapy alone.
Among completers who provided 1-year data, all statistically significant differences between the CBT and light therapy groups persisted after adjustment for ongoing treatment with light therapy, antidepressants, and
If these findings are replicated, CBT could represent a more effective, practical, and palatable approach to long-term SAD management than light therapy.