The measurement tools used were the the SAS questionnaire for anxiety and the BECK-II questionnaire for depression, in addition to collecting two biological markers - saliva cortisol and saliva amylase.
Changes in mean anxiety score and mean depression score in the guided imagery/PMR intervention group were significantly higher than the changes in the control group (b = -29.4, p < 0.001; b = -29.4, p < 0.001, resp.) which were not.
Additionally, the guided imagery group's cortisol levels before the intervention (0.30 ± 0.25) gradually dropped up to week 3 (0.16 ± 0.18), while the control group's cortisol levels before the intervention (0.21 ± 0.22) gradually increased up to week 3 (0.44 ± 0.35). The same interaction appears for the Amylase levels (p < 0.001).
The investigators conclude that patients with prostate and breast cancer undergoing chemotherapy treatment can benefit from PMR and GI sessions to reduce their anxiety and depression.
Citation: Andreas Charalambous, Margarita Giannakopoulou, Evangelos Bozas, and Lefkios Paikousis. Evidence Based Complementary and Alternative Medicine. 2015;2015:270876. doi: 10.1155/2015/270876. Epub 2015 Aug 6.
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