Guided Imagery and Meditation Blog | Health Journeys

You are here: Home Hot Research Regulation of hypothalamic-pituitary-adrenal activity in response to cognitive therapy in patients

Regulation of hypothalamic-pituitary-adrenal activity in response to cognitive therapy in patients

11 Jul
A clinical trial from researchers at the Department of Psychiatry and Neurosciences of Maimonides University in Buenos Aires, Argentina, evaluated the effectiveness of cognitive therapy (CT) in the treatment of generalized anxiety disorder (GAD), as reflected through both psychological and psychoneuroendocrinological measures.

Outpatients with GAD were treated with CT for up to a maximum of 24 sessions. Anxiety-related symptoms were evaluated according to the Hamilton Anxiety Rating Scale (HAM-A), and the hypothalamic-pituitary-adrenal (HPA) function was determined through assessment of circulating cortisol levels.
A significant decrease in the HAM-A scores, along with significant changes in plasma cortisol levels, were observed after completion of treatment with CT. These observations demonstrate that the effect of certain psychotherapeutic approaches, such as CT, may be observed at both psychological and biological levels.

Citation: Tafet GE, Feder DJ, Abulafia DP, Roffman SS. Regulation of hypothalamic-pituitary-adrenal activity in response to cognitive therapy in patients with generalized anxiety disorder. Cognitive, affective & behavioral neuroscience.. 2005 Mar; 5 (1): pages 37-40.
Belleruth Naparstek

Psychotherapist, author and guided imagery pioneer Belleruth Naparstek is the creator of the popular Health Journeys guided imagery audio series. Her latest book on imagery and posttraumatic stress, Invisible Heroes: Survivors of Trauma and How They Heal (Bantam Dell), won the Spirituality & Health Top 50 Books Award